Shortly after the introduction of CT scanning of the thorax, von Eiff and colleagues showed in leukaemia patients, that initiation of antifungal treatment within the first 10 days of infection reduced mortality from 90% to 40% ...
A 14 year review of autopsies in a German teaching hospital with a high autopsy rate (70%) and use of specific stains for invasive fungal infection, showed that 60% of those with invasive disease at autopsy were not diagnosed before death...
In common with other drug developments, antifungal drug development is a costly and time-consuming business.
Additionally, patients at risk of invasive fungal infection, or infected by Aspergillus, Candida, Cryptococcus, Mucorales
and other pathogenic fungi, can come from many different patient populations...
A selection of posters, a webinar and algorithms are available to download below in PDF format.